Familial Vizsla Polymyositis
Familial polymyositis involving muscle cell degeneration, necrosis, and apoptosis has been described in Vizsla dogs. It is thought to be mediated by cytotoxic lymphocyte mechanisms.
Age of Onset: Any age of animal can be affected
Sex Predisposition: Any sex of animal can be affected
Clinical Course:
Variable
Variable
Clinical Signs:
Posture and Appearance
Exophthalmos
Thin appearance (due to loss of muscle mass)
Movement
Generalized weakness
“Stiff” gait (shorter interstep distance and limbs in a more extended posture)
Cranial Nerves
Inability to open jaw
Special Functions (e.g. respiration; urination)
Megaesophagus
Dysphagia
Dysphonia
Muscle Atrophy
Generalized muscle atrophy
Masticatory muscle atrophy
Pain Sensation
May have muscle pain on palpation
Other
Fever
Posture and Appearance
Exophthalmos
Thin appearance (due to loss of muscle mass)
Movement
Generalized weakness
“Stiff” gait (shorter interstep distance and limbs in a more extended posture)
Cranial Nerves
Inability to open jaw
Special Functions (e.g. respiration; urination)
Megaesophagus
Dysphagia
Dysphonia
Muscle Atrophy
Generalized muscle atrophy
Masticatory muscle atrophy
Pain Sensation
May have muscle pain on palpation
Other
Fever
Diffuse muscle
Unknown
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