Leukodystrophy
Leukodystrophy is a generalized progressive degenerative vacuolation of white matter of the central nervous system
Age of Onset: Less than 4 weeks of age
Sex Predisposition: Any sex of animal can be affected
Clinical Course:
Clinical signs worsen over time
Clinical signs worsen over time
Clinical Signs:
Behavioral/Mental Awareness
Seizures
Apathy
Movement
Ataxia
Hypermetria
Intention or generalized tremor
Circling
Non-ambulatory tetraparesis
Proprioception
Absent postural reactions
Cranial Nerves
Head tilt
Ventral stabismus
Special Functions (e.g. respiration; urination)
Dysphoric vocalization
Dysphagia
Other
Sudden death
Behavioral/Mental Awareness
Seizures
Apathy
Movement
Ataxia
Hypermetria
Intention or generalized tremor
Circling
Non-ambulatory tetraparesis
Proprioception
Absent postural reactions
Cranial Nerves
Head tilt
Ventral stabismus
Special Functions (e.g. respiration; urination)
Dysphoric vocalization
Dysphagia
Other
Sudden death
Diffuse intracranial
Autosomal recessive TSEN54 gene mutation
For breed specific genetic testing, click the link below:
www.genimal.com/dna-tests/dog/leukodystrophy-in-schnauzer/?tab=description
www.animalabs.com/shop/dog/leukoencephalopathy-lep--leukodystrophy-ld--schnauzer-type/
For breed specific genetic testing, click the link below:
www.genimal.com/dna-tests/dog/leukodystrophy-in-schnauzer/?tab=description
www.animalabs.com/shop/dog/leukoencephalopathy-lep--leukodystrophy-ld--schnauzer-type/
To read more about this disease click below:
