(Cerebellar) Neuroaxonal Dystrophy
Neuroaxonal dystrophy is a progressive disorder of the cerebellum system.
Age of Onset: 6 months to 1 year of age
Sex Predisposition: Any sex of animal can be affected
Clinical Course:
Clinical signs worsen over 2-4 years
Clinical signs worsen over 2-4 years
Clinical Signs:
Behavioral/Mental Awareness
Changes in behavior (dull, nervous, increased vocalization)
Compulsory pacing
Movement
Ataxia
Hypermetria
Head (Intention) tremor
Proprioception
Proprioceptive deficits
Cranial Nerves
Menace deficit
Visual defecii
Nystagmus (resting and/or positional)
Special functions (e.g. respiration; urination)
Urinary incontinence
Fecal incontinence
Muscle Atrophy
Reduced muscle tone
Behavioral/Mental Awareness
Changes in behavior (dull, nervous, increased vocalization)
Compulsory pacing
Movement
Ataxia
Hypermetria
Head (Intention) tremor
Proprioception
Proprioceptive deficits
Cranial Nerves
Menace deficit
Visual defecii
Nystagmus (resting and/or positional)
Special functions (e.g. respiration; urination)
Urinary incontinence
Fecal incontinence
Muscle Atrophy
Reduced muscle tone
Diffuse intracranial (cerebrum, cerebellum, brainstem)
Autosomal recessive TECPR2 gene mutation
For breed-specific genetic testing, click the link(s) below:
www.genomia.cz/en/test/nad-swd/
www.laboklin.co.uk/laboklin/showGeneticTest.jsp?testID=8287
For breed-specific genetic testing, click the link(s) below:
www.genomia.cz/en/test/nad-swd/
www.laboklin.co.uk/laboklin/showGeneticTest.jsp?testID=8287
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