Granulomatous Meningoencephalomyelitis (GME) / Primary Reticulosis
An idiopathic inflammatory response characterized by mesenchymal derived cellular infiltration into the white matter of the brain and spinal cord.
Age of Onset: 9 months – 10 years of age
Sex Predisposition: Any sex of animal can be affected
Clinical Course:
Clinical signs worsen over time
Clinical signs worsen over time
Clinical Signs:
Behavioral/Mental Awareness
Decreased awareness
“Depression”
Seizures
Posture and Appearance
Postural defects
Movement
Ataxia
Falling
Circling
Paralysis
Paresis
Increased tone in all 4 limbs
Proprioception
Cranial Nerves
Facial nerve palsy
Head tilt
Nystagmus
Strabismus
Visual defects
Spinal Reflexes
Postural reflex deficits
Special Reflexes (e.g. cutaneous trunci)
Absent menace reflex
Decreased pupillary response
Special Functions (e.g. respiration; urination)
Anorexia
Salivation
Vomiting
Other
Allotriophagia
Behavioral/Mental Awareness
Decreased awareness
“Depression”
Seizures
Posture and Appearance
Postural defects
Movement
Ataxia
Falling
Circling
Paralysis
Paresis
Increased tone in all 4 limbs
Proprioception
Cranial Nerves
Facial nerve palsy
Head tilt
Nystagmus
Strabismus
Visual defects
Spinal Reflexes
Postural reflex deficits
Special Reflexes (e.g. cutaneous trunci)
Absent menace reflex
Decreased pupillary response
Special Functions (e.g. respiration; urination)
Anorexia
Salivation
Vomiting
Other
Allotriophagia
Brain and spinal cord
Unknown
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