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Idiopathic Eosinophilic Meningoencephalitis
  • Description
  • Signalment
  • Clinical Features
  • Neurolocalization
  • Genetics
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Idiopathic infiltration of eosinophils into central nervous system structures resulting in damage and inflammation.
Age of Onset: 4 months - 5.5 years of age
Sex Predisposition: Males are more likely to be affected
Clinical Course:
​Clinical signs may worsen over time
Clinical Signs:
Behavioral/Mental Awareness
Behavioral abnormalities
Depression
Seizures
Somnolence

Posture and Appearance
All 4 limbs in rigid extension
Deviation of the head to the right
Generalized muscle tremors
Torticollis to the right

Movement
Circling
Collapse 
Head pressing
Mild ataxia
Pacing
Tetraparesis

Proprioception
Deficits in all limbs

Cranial Nerves
Anisocoria
Mildly contracted facial muscles
Visual impairment
Decreased menace response 

Special Reflexes (e.g. cutaneous trunci)
Decreased gag reflex
​
Painful Reactions
Manipulation of the front limbs
Palpation of cervical spine
Palpation of thoracic spine

Other
Decreased appetite
Excessive salivation
Hypersensitivity to touch and sound
Brain and spinal cord
Unknown
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References
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