Sensory Neuropathy
Peripheral neuropathies can involve either the sensory or motor systems, or both. Sensory neuropathies involve exclusively or predominantly sensory nerve cells with minor involvement of motor neurons. With this disorder, there may also be concomitant autonomic signs.
Age of Onset: 2-3 months of age
Sex Predisposition: Any sex of animal can be affected
Clinical Course:
Clinical signs worsen over time with pelvic limbs being more severely affected compared to thoracic limbs
Clinical signs worsen over time with pelvic limbs being more severely affected compared to thoracic limbs
Clinical Signs:
Behavioral/Mental Awareness
Self-mutilation to distal limbs
Movement
Progressive paresis in the pelvic and thoracic limbs
Ataxia
Limb hyperextension
Proprioception
General proprioceptive deficits to the pelvic limbs and thoracic limbs
Knuckling over of feet
Crossing of hindlimbs
Cranial Nerves
Reduced palpebral reflex
Spinal Reflexes
Reduced patellar reflex
Reduced pedal reflex
Reduced withdrawal reflex
Special Reflexes (e.g. cutaneous trunci)
Reduced to absent cutaneous trunci reflex
Reduced to absent anal reflex (with normal anal tone)
Special Functions (e.g. respiration; urination)
Urinary incontinence (urine dribbling)
Regurgitation
Muscle Atrophy
Masticatory muscle atrophy (in 1 dog)
Pain Sensation
Absent superficial skin sensation in all distal limbs, ventral trunk, and head (with the exception of the lips and inside of the nostril)
Behavioral/Mental Awareness
Self-mutilation to distal limbs
Movement
Progressive paresis in the pelvic and thoracic limbs
Ataxia
Limb hyperextension
Proprioception
General proprioceptive deficits to the pelvic limbs and thoracic limbs
Knuckling over of feet
Crossing of hindlimbs
Cranial Nerves
Reduced palpebral reflex
Spinal Reflexes
Reduced patellar reflex
Reduced pedal reflex
Reduced withdrawal reflex
Special Reflexes (e.g. cutaneous trunci)
Reduced to absent cutaneous trunci reflex
Reduced to absent anal reflex (with normal anal tone)
Special Functions (e.g. respiration; urination)
Urinary incontinence (urine dribbling)
Regurgitation
Muscle Atrophy
Masticatory muscle atrophy (in 1 dog)
Pain Sensation
Absent superficial skin sensation in all distal limbs, ventral trunk, and head (with the exception of the lips and inside of the nostril)
Peripheral nervous system
Unknown
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