Hereditary Ataxia/Spinocerebellar Ataxia
Hereditary ataxia is a degenerative spinal disease affecting spinal cord white matter, central auditory pathways, and peripheral nerves.
Age of Onset: 2-6 months of age
Sex Predisposition: Any sex of animal can be affected
Clinical Course:
Clinical signs progressed for a period of time then became stable
Clinical signs progressed for a period of time then became stable
Clinical Signs:
Behavioral/Mental Awareness
Abnormal vocalization
Aggression
Anxiety
Excess facial rubbing
Seizures
Posture and Appearance
Myokymia
Movement
Ataxia
Hypermetria
Incoordination
Intention tremor
Myotonia
Paresis
Prancing/dancing gait
Weakness
Proprioception
Decreased postural reflexes
Cranial Nerves
Absent/decreased menace response
Spinal Reflexes
Exaggerated spinal reflexes
Behavioral/Mental Awareness
Abnormal vocalization
Aggression
Anxiety
Excess facial rubbing
Seizures
Posture and Appearance
Myokymia
Movement
Ataxia
Hypermetria
Incoordination
Intention tremor
Myotonia
Paresis
Prancing/dancing gait
Weakness
Proprioception
Decreased postural reflexes
Cranial Nerves
Absent/decreased menace response
Spinal Reflexes
Exaggerated spinal reflexes
Spinal cord
Autosomal recessive KCNJ10 gene mutation
For breed specific genetic testing, follow the link below:
https://vgl.ucdavis.edu/test/cerebellar-ataxia-ca-spinone-italiano
https://labogen.com/en/genetic-diseases-dog/cerebellar-ataxia-ca-italian-spinone/
For breed specific genetic testing, follow the link below:
https://vgl.ucdavis.edu/test/cerebellar-ataxia-ca-spinone-italiano
https://labogen.com/en/genetic-diseases-dog/cerebellar-ataxia-ca-italian-spinone/
To read more about this disease click below:
