Multisystem Axonopathy and Neuronopathy
A unique dysfunction of the nervous system involving degeneration of both sensory and motor tracts of the spinal cord.
Age of Onset: 5 - 7 months of age
Sex Predisposition: Any sex of animal can be affected
Clinical Course:
Clinical signs worsen over several weeks
Clinical signs worsen over several weeks
Clinical Signs:
Posture and Appearance
Kyphotic posture
Cyanotic
Movement
Weakness
Tetraparesis
Resting high-frequency, low amplitude muscle tremors in all limbs
Tremors elicited by palpation of the limb muscles
Spinal Reflexes
Decreased/Absence flexor and patellar reflexes
Muscle Atrophy
Generalized muscle atrophy
Other
Tachypneic
Dyspneic
Pyrexia
Posture and Appearance
Kyphotic posture
Cyanotic
Movement
Weakness
Tetraparesis
Resting high-frequency, low amplitude muscle tremors in all limbs
Tremors elicited by palpation of the limb muscles
Spinal Reflexes
Decreased/Absence flexor and patellar reflexes
Muscle Atrophy
Generalized muscle atrophy
Other
Tachypneic
Dyspneic
Pyrexia
Spinal cord
Unknown
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