Glycogenosis Type III (GM3)
Glycogenosis Type III causes a deficiency in an enzyme which causes defects in the catabolism of glycogen resulting in its accumulation in neuron lysosomes and cytoplasm.
Age of Onset: 2 weeks – 12 months of age
Sex Predisposition: Any sex of animal can be affected
Clinical Course:
Clinical signs worsen over time
Clinical signs worsen over time
Clinical Signs:
Behavioral/Mental Awareness
“Depression”
Dizziness
Difficulty rising
Posture and Appearance
Growth retardation
Movement
Muscle weakness
Ataxia
Special Functions (e.g. respiration; urination)
Abdominal distention due to hepatomegaly
Polydipsia
Behavioral/Mental Awareness
“Depression”
Dizziness
Difficulty rising
Posture and Appearance
Growth retardation
Movement
Muscle weakness
Ataxia
Special Functions (e.g. respiration; urination)
Abdominal distention due to hepatomegaly
Polydipsia
Brain and spinal cord
Autosomal recessive
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