VNDD
  • Home
  • Search
  • Methodology
  • Contact
<Return to Disease List
Cerebellar Ataxia (Cerebellar Abiotrophy/Cerebellar Cortical Abiotrophy/Cerebellar Cortical Degeneration/Cerebellar Degeneration)
  • Description
  • Signalment
  • Clinical Features
  • Neurolocalization
  • Genetics
<
>
Cerebellar abiotrophy results from a loss of vital substance for continued life of the neuron. Many of these diseases are associated with loss of purkinje cells.
Age of Onset: 1-3 months of age
Sex Predisposition: Any sex of animal can be affected
Clinical Course:
​Clinical signs typically worsen over time
Clinical Signs:
Behavioral/Mental Awareness  
Incessant crying

Posture and Appearance  
Periodic opisthotonus
Vertical nystagmus
Positional nystagmus

Movement 
Hypermetria
Inability to stand
Ataxia
Rolling on side
Unable to remain in a sternal position
Intention tremor
Dysmetria
Mild spasticity
“lurching” or forward-falling movements
Staggering
Falling


Proprioception  
Proprioceptive deficits
Cerebellum
Autosomal recessive SEL1L gene mutation

For breed specific genetic testing, click the link below:
www.eurovetgene.com/cerebellar-ataxia-finnish-hound
​www.animalabs.com/shop/finnish-hound/cerebellar-ataxia-finnish-hound-type-fhacafh/

https://www.laboklin.co.uk/laboklin/showGeneticTest.jsp?testID=8537
​​www.genomia.cz/en/test/cerebellar-ataxia-sel1l/
To read more about this disease click below:
References
Picture
Contact us:
[email protected]

Privacy Policy
Terms and Conditions​
Cookie Policy
Disclaimer
  • Home
  • Search
  • Methodology
  • Contact