Polioencephalomyelopathy
Polioencephalomyelopathy is a progressive neurodegenerative disorder primarily affecting the gray matter of the brain and spinal cord.
Age of Onset: 2-6 months of age
Sex Predisposition: Any sex of animal can be affected
Clinical Course:
Movement disordere episodes occur with excess stimulation, ecitement, and loud noises. The frequency and severity of signs icrease over tiem
Movement disordere episodes occur with excess stimulation, ecitement, and loud noises. The frequency and severity of signs icrease over tiem
Clinical Signs:
Movement
Spastic tetraparesis (extensor tone of thoracic limbs > pelvic limbs)
Episodes of ataxia and hypermetria/dystonia of the thoracic limbs
Fatigue after movement, progressing to recumbency
Cranial Nerves
Divergent strabismus
Reduced vision
Head-tilt
Movement
Spastic tetraparesis (extensor tone of thoracic limbs > pelvic limbs)
Episodes of ataxia and hypermetria/dystonia of the thoracic limbs
Fatigue after movement, progressing to recumbency
Cranial Nerves
Divergent strabismus
Reduced vision
Head-tilt
Brain and spinal cord
Association with autosomal recessive MECR gene mutation
For breed specific genetic testing, click the link below:
https://www.genomia.cz/en/test/kombi-eurasier/
https://www.laboklin.co.uk/laboklin/showGeneticTest.jsp?testID=8965
For breed specific genetic testing, click the link below:
https://www.genomia.cz/en/test/kombi-eurasier/
https://www.laboklin.co.uk/laboklin/showGeneticTest.jsp?testID=8965
To read more about this disease click below:
