Exercise-Induced Collapse/Exercise-Induced Hyperthermia Syndrome (Canine Stress Syndrome)
Malignant hyperthermia is typically associated with exposure to succinylcholine or volatile anesthetic agents. English Springer Spaniel dogs have been noted to experience signs similar to malignant hyperthermia following mild-to-moderate exercise.
Age of Onset: 4 months - 7 years of age
Sex Predisposition: Males may be more commonly affected
Clinical Course:
Clinical signs tend to present acutely after episodes of strenuous activity. Both gait and mentation typically return to normal within 30 minutes of onset.
Clinical signs tend to present acutely after episodes of strenuous activity. Both gait and mentation typically return to normal within 30 minutes of onset.
Clinical Signs:
Behavioral/Mental Awareness
Dull mentation
Disorientation
Posture and Appearance
Hemorrhage
Movement
Falling
Exaggerated lifting of each limb while walking
Choppy gait
Ataxia
Delayed limb protraction
Proprioception
Dragging pelvic and/or thoracic limbs
Cranial Nerves
Absent menace response
Delayed PLR
Spinal Reflexes
Increased extensor tone
Special Functions (e.g. respiration; urination)
Dyspnea (rapid, laborous, stertorous respiration)
Other
Hyperthermia
Seizures
Behavioral/Mental Awareness
Dull mentation
Disorientation
Posture and Appearance
Hemorrhage
Movement
Falling
Exaggerated lifting of each limb while walking
Choppy gait
Ataxia
Delayed limb protraction
Proprioception
Dragging pelvic and/or thoracic limbs
Cranial Nerves
Absent menace response
Delayed PLR
Spinal Reflexes
Increased extensor tone
Special Functions (e.g. respiration; urination)
Dyspnea (rapid, laborous, stertorous respiration)
Other
Hyperthermia
Seizures
Diffuse neuromuscular
Suspected X-linked recessive disorder
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