Neurofibrillary Accumulation
Neurofibrillary accumulation is a degenerative disease characterized by the accumulation of neurofibril protein in the cytoplasm of neurons.
Age of Onset: 12 weeks of age
Sex Predisposition: Any sex of animal can be affected
Clinical Course:
Clinical signs progress over time
Clinical signs progress over time
Clinical Signs:
Movement
Weakness
Difficulty rising
Collapse
Proprioception
Collapsed when hopped
Cranial Nerves
Absent menace response
Absent PLR bilaterally
Spinal Reflexes
Absent or reduced patellar reflexes
Movement
Weakness
Difficulty rising
Collapse
Proprioception
Collapsed when hopped
Cranial Nerves
Absent menace response
Absent PLR bilaterally
Spinal Reflexes
Absent or reduced patellar reflexes
Brain
Unknown
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