Cerebellar Abiotrophy/Cerebellar Cortical Abiotrophy/Cerebellar Cortical Degeneration/Cerebellar Degeneration
Cerebellar abiotrophy results from a loss of vital substance for continued life of the neuron. Many of these diseases are associated with loss of purkinje cells.
Age of Onset: Clinical signs may be present from birth to 6 months of age
Sex Predisposition: Any sex of animal can be affected
Clinical Course:
Clinical signs typically worsen over time
Clinical signs typically worsen over time
Clinical Signs:
Posture and Appearance
Periodic opisthotonus
Movement
Hypermetria
Pelvic limb stiffness
Inability to stand
Ataxia
Rolling on side
Intention tremor
Dysmetria
“lurching” or forward-falling movements
Staggering
Falling
Loss of muscle tone
Proprioception
Proprioceptive deficits
Cranial Nerves
Absent menace response
Vertical nystagmus
Positional nystagmus
Posture and Appearance
Periodic opisthotonus
Movement
Hypermetria
Pelvic limb stiffness
Inability to stand
Ataxia
Rolling on side
Intention tremor
Dysmetria
“lurching” or forward-falling movements
Staggering
Falling
Loss of muscle tone
Proprioception
Proprioceptive deficits
Cranial Nerves
Absent menace response
Vertical nystagmus
Positional nystagmus
Cerebellum
Unkown
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