Leukodystrophy (Oligodendroglial dysplasia)
Leukodystrophies are a group of hereditary disorders affecting the central nervous system.
Age of Onset: 2-9 weeks of age
Sex Predisposition: Any sex of animal can be affected
Clinical Course:
Clinical signs worsen over the course fo several months to years
Clinical signs worsen over the course fo several months to years
Clinical Signs:
Behavioral/Mental Awareness
Seizures
Movement
Generalized whole body tremors
Ataxia
Paresis to paralysis
Limb spasticity
Proprioception
Absent postural reactions
Sponal Reflexes
Increased to normal spinal reflexes
Behavioral/Mental Awareness
Seizures
Movement
Generalized whole body tremors
Ataxia
Paresis to paralysis
Limb spasticity
Proprioception
Absent postural reactions
Sponal Reflexes
Increased to normal spinal reflexes
White matter of the brainstem and spinal cord
Unknown
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