Progressive Axonopathy (Sensory Neuronopathy of Boxers)
Sensory neuropathy is an inherited progressive neuropathy of that preferentially involves the sensory components of the peripheral nervous system
Age of Onset: Less than 6 months of age
Sex Predisposition: Any sex of animal can be affected
Clinical Course:
Clinical signs begin in the pelvic limbs and progress to involve the thoracic limbs. Clinical signs progress for 12-18 months and then plateau.
Clinical signs begin in the pelvic limbs and progress to involve the thoracic limbs. Clinical signs progress for 12-18 months and then plateau.
Clinical Signs:
Movement
Ataxia
Paresis (paraparesis to tetraparesis)
Hypermetria
Proprioception
Reduced proprioception
Spinal Reflexes
Decreased muscle tone
Hyporeflexia/areflexia
Muscle Atrophy
No muscle atrophy
Movement
Ataxia
Paresis (paraparesis to tetraparesis)
Hypermetria
Proprioception
Reduced proprioception
Spinal Reflexes
Decreased muscle tone
Hyporeflexia/areflexia
Muscle Atrophy
No muscle atrophy
Diffuse neuromuscular
Autosomal recessive inheritance
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