Distal Sensorimotor Polyneuropathy
Late onset laryngeal paralysis and polyneuropathy is an idiopathic disease of older large breed dogs resulting in progressive “length-dependent” degeneration of neurons.
Age of Onset: 1-3 years of age
Sex Predisposition: Any sex of animal can be affected
Clinical Course:
Clinical signs worsen over time
Clinical signs worsen over time
Clinical Signs:
Behavioral/Mental Awareness
Exercise-intolerance
Posture and Appearance
Plantigrade stance
Movement
Tetraparesis
Proprioception
Postural reaction deficits
Spinal Reflexes
Reduced to absent patellar reflexes
Absent cutaneous trunci reflex
Reduced to absent withdrawal reflexes
Cranial Nerves
Reduced palpebral closure
Muscle Atrophy
Appendicular muscle atrophy
Decreased muscle tone
Behavioral/Mental Awareness
Exercise-intolerance
Posture and Appearance
Plantigrade stance
Movement
Tetraparesis
Proprioception
Postural reaction deficits
Spinal Reflexes
Reduced to absent patellar reflexes
Absent cutaneous trunci reflex
Reduced to absent withdrawal reflexes
Cranial Nerves
Reduced palpebral closure
Muscle Atrophy
Appendicular muscle atrophy
Decreased muscle tone
Peripheral nerves
Unknown
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