Cerebellar Vermis Agenesis (Dandy Walker Syndrome)
Congenital malformations of the cerebellum with caudal vermian hypoplasia is described, with some dogs having associated ventricular dilation (Dandy-Walker malformation). This is a rare congenital malformation that shares similarities with the human form of the disease. It consists of a triad of congenital anomalies including cerebellar vermian hypoplasia, communicating hydrocephalus, and the presence of a fluid-filled cyst (syrinx) within the posterior fossa.
Age of Onset: 2 weeks - 3 months of age
Sex Predisposition: Any sex of animal can be affected
Clinical Course:
Clinical signs typically did not worsen over time
Clinical signs typically did not worsen over time
Clinical Signs:
Behavioral/Mental Awareness
Listless
Movement
Ataxia
Hypermetria
Intention tremors
Bunny hopping gait
Increased extensor tone of the thoracic limbs
Cranial Nerves
Vestibular signs (head tilt, circling, nystagmus)
Absent menace response
Behavioral/Mental Awareness
Listless
Movement
Ataxia
Hypermetria
Intention tremors
Bunny hopping gait
Increased extensor tone of the thoracic limbs
Cranial Nerves
Vestibular signs (head tilt, circling, nystagmus)
Absent menace response
Intracranial - Cerebellum
Unknown
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