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Narcolepsy/Cataplexy
  • Description
  • Signalment
  • Clinical Features
  • Neurolocalization
  • Genetics
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Narcolepsy is described as "inappropriate daytime sleepiness" and often animals are presented for "falling asleep" during times of excitement, such as while eating or when exhibiting play behavior. Cataplexy is a sudden, temporary loss of muscle control that often accompanies narcolepsy.
Age of Onset: 4-6 weeks of age
Sex Predisposition: Any sex of animal can be affected
Clinical Course:
Clinical signs may worsen during the first year of life and then gradually decline in frequency and severity. Narcoleptic episodes are typically exacerbated by emotional stimuli such as during eating or times of play.
Clinical Signs:
Behavioral/Mental Awareness 
Shortened sleep latency 
“Sleepy”
Cannot maintain long stretches of wakefulness 
Fall asleep faster than normal  
No loss of consicousnesss


Posture and Appearance
Attacks of flaccid paralysis (cataplexy)
​Eyes typically remain open during narcoleptic episodes
Intracranial
Autosomal recessive inheritance (HCRTR2 mutation)
*Genetic testing for narcolepsy is only available for Doberman, Labrador Retriever, and Dachshund breeds
To read more about this disease click below:
References
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