Polioencephalomyelopathy
Polioencephalomyelopathy is a progressive neurodegenerative disorder primarily affecting the gray matter of the brain and spinal cord.
Age of Onset: 5 months - 1 year
Sex Predisposition: Any sex of animal can be affected
Clinical Course:
Clinical signs worsen over the course of several months progressing from psychomotor seizures to recumbency
Clinical signs worsen over the course of several months progressing from psychomotor seizures to recumbency
Clinical Signs:
Behavioral/Mental Awareness
Psycho-motor seizures
Otherwise normal mentation
Movement
Spastic tetraparesis (extensor tone of thoracic limbs > pelvic limbs)
Fatigue after movement, progressing to recumbency
Ataxia
Cranial Nerves
Positional nystagmus
Head-tilt
Facial twitching
Spinal Reflexes
Patellar hyporeflexia to areflexia
Muscle Atrophy
Diffuse appendicular muscle atrophy
Behavioral/Mental Awareness
Psycho-motor seizures
Otherwise normal mentation
Movement
Spastic tetraparesis (extensor tone of thoracic limbs > pelvic limbs)
Fatigue after movement, progressing to recumbency
Ataxia
Cranial Nerves
Positional nystagmus
Head-tilt
Facial twitching
Spinal Reflexes
Patellar hyporeflexia to areflexia
Muscle Atrophy
Diffuse appendicular muscle atrophy
Brain and spinal cord
Unknown
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