Meningoencephalitis of Unknown Origin (MUO)
Meningoencephalitis of unknown origin is characterized by immune-mediated inflammation of the central nervous system with no identifiable cause.
Age of Onset: Any age of animal can be affected
Sex Predisposition: Any sex of animal can be affected
Clinical Course:
Clinical signs may worsen over time
Clinical signs may worsen over time
Clinical Signs:
Behavioral/Mental Awareness
Abnormal vocalization
Aggression
Decreased mentation
“Dull”
Excitation
Restlessness
Seizures
Sleepiness (Narcolepsy/cataplexy)
Movement
Ataxia
Circling
Paresis
Tremors
Weakness
Proprioception
Paw placement deficits
Cranial Nerves
Blindness
Cranial nerve deficits
Vestibular signs (Nystagmus, head tilt)
Absent gag reflex
Reduced menace response
Miosis
Painful Reactions
Pain on palpation of the cervical spine
Behavioral/Mental Awareness
Abnormal vocalization
Aggression
Decreased mentation
“Dull”
Excitation
Restlessness
Seizures
Sleepiness (Narcolepsy/cataplexy)
Movement
Ataxia
Circling
Paresis
Tremors
Weakness
Proprioception
Paw placement deficits
Cranial Nerves
Blindness
Cranial nerve deficits
Vestibular signs (Nystagmus, head tilt)
Absent gag reflex
Reduced menace response
Miosis
Painful Reactions
Pain on palpation of the cervical spine
Intracranial
Unknown
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