Hereditary Polyneuropathy/Neuropathy
Hereditary polyneuropathy/neuropathy is an idiopathic degeneration of nerves often characterized by axonal degeneration and hypomyelination.
Age of Onset: 8-9 years of age
Sex Predisposition: Any sex of animal can be affected
Clinical Course:
Clinical signs worsen over time, primarily affecting the branches of the sciatic nerve
Clinical signs worsen over time, primarily affecting the branches of the sciatic nerve
Clinical Signs:
Movement
Collapse
Hyporeflexia
Progressive paraparesis
Proprioception
Proprioceptive deficits
Spinal Reflexes
Decreased spinal reflexes
Decreased patellar reflex
Special Functions (e.g. respiration; urination)
Exercise intolerance
Muscle Atrophy
General muscle atrophy
Other
Abnormal vocalization
Hyperesthesia
Movement
Collapse
Hyporeflexia
Progressive paraparesis
Proprioception
Proprioceptive deficits
Spinal Reflexes
Decreased spinal reflexes
Decreased patellar reflex
Special Functions (e.g. respiration; urination)
Exercise intolerance
Muscle Atrophy
General muscle atrophy
Other
Abnormal vocalization
Hyperesthesia
Peripheral nerve
Autosomal recessive inheritance
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