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Craniomandibular Osteopathy​ (CMO)
  • Description
  • Signalment
  • Clinical Features
  • Neurolocalization
  • Genetics
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​Craniomandibular osteopathy results from an abnormal non-neoplastic proliferation of the bones of the cranium.
Age of Onset: Less than 1 year old
Sex Predisposition: Any sex of animal can be affected
Clinical Course:
​Clinical signs progress over a short period of time
​
Clinical signs refer to the predominant location of bony growth and subsequent compression of neural tissue. In this case, involvement of the occipital, frontal, parietal, temporal, and maxillary bones resulted in severe compression of the cerebellum and brainstem. In addition, the Akita in this report also had generalized long bone involvement which is not a typical manifestation of CMO (Ratteree, et al., 2011).
Clinical Signs:
Behavioral/Mental Awareness
Head shy
Failure to thrive


Posture and Appearance
Difficulty opening the jaw
Facial swelling
Enlargement of the jaw


Movement
Mild ataxia

Proprioception
Proprioceptive deficits

Cranial Nerve
Lack of response to audible stimuli

Special Functions
Difficulty with prehension
Excessive drooling

Painful Reactions
Painful on palpation of the side of the face and dorsal aspect of the face
​Pain when opening the mouth or eating


Other
Lymphadenomegaly (mandibular and medial retropharyngeal)
Crepitus and joint laxity in the shoulder, elbow, coxofemoral, stifle, and tarsal joints
Appendicular orthopedic abnormalities
Cranium and mandible
Unknown
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References
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